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Reproduction Collaboratory

Contact:  Kim Wallen, PhD,, Ph. 404-727-4125

At A Glance

The Reproduction Collaboratory has made significant discoveries about sexual behavior in five major areas: the medial amygdala, estrogens, energetics, steroid responsiveness and sex differences. Discoveries include:

  • Phytoestrogen supplements, an increasingly popular soy-derived alternative to estrogen replacement therapy, do not produce the same molecular and behavioral effects on the brain as endogenous estrogen and can actually have anti-estrogenic effects on female sexual behavior.
  • Medroxyprogesterone acetate, a synthetic form of the naturally occurring steroid hormone progesterone widely used in contraceptives and hormone replacement therapy, increases aggression and anxiety and reduces sexual activity in female monkeys.
  • Caenorhabditis elegans, a hermaphroditic self-fertilizing nematode, produces a pheromone that appears to regulate the male sex drive.
  • Food restriction significantly suppresses both reproductive and maternal behaviors in rodents.
  • Visual sexual stimuli produce much higher levels of activation in the amygdala of the male brain than the female brain.

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